Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ TGF-β RI Kinase Inhibitor V
The TGF-β RI Kinase Inhibitor V, also referenced under CAS 627536-09-8, controls the biological activity of TGF-β RI. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ AG 17
Anti-proliferative agent that acts as a selective inhibitor of the platelet-derived growth factor receptor tyrosine kinase (IC50 = 500 nM).
MilliporeSigma™ Calbiochem™ AG 9
An inactive compound that can be used as a negative control for inhibition of EGFR (IC50 >1250 μM for EGFR kinase).
MilliporeSigma™ Calbiochem™ Okadaic Acid, Prorocentrum sp.
Okadaic Acid, CAS 78111-17-8, is a highly potent inhibitor of protein phosphatase 1 (IC50 = 10-15 nM) and 2A (IC50 = 0.1 nM).
MilliporeSigma™ Calbiochem™ Anthrax Lethal Factor, Recombinant, Bacillus anthracis, B. anthracis
Recombinant, Bacillus anthracis anthrax lethal factor expressed in a specialized strain of B.
MilliporeSigma™ Calbiochem™ InSolution™ TLR4 Inhibitor, TAK-242
A 25 mM (2 mg/221 μL) sterile-filtered solution of TLR4 Inhibitor, TAK-242 in DMSO.
MilliporeSigma™ Calbiochem™ NSC 721648
A cell-permeable benzothiazole compound that exhibits potent in vitro antiproliferative activity against HCC 2998, IGROV1, MCF-7, MDA 468, SR, and T-47D.
MilliporeSigma™ Calbiochem™ Ifenprodil Hemitartrate
A partial non-competitive antagonist highly selective for GluN1/N2B subtype NMDA receptors (IC50
MilliporeSigma™ Calbiochem™ DNA Repair Pathway Inhibitor, NS-123
The DNA Repair Pathway Inhibitor, NS-123, also referenced under CAS 101860-83-7, modulates DNA Repair Pathway. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Bethanechol Chloride
Bethanechol Chloride is an agonist selective for Muscarinic Acetylcholine Receptors with no effect on nicotinic receptors.
MilliporeSigma™ Calbiochem™ Dopamine Receptor Antagonist II, Thioridazine, HCl
The Dopamine Receptor Antagonist II, Thioridazine, HCl, also referenced under CAS 130-61-0, controls the biological activity of Dopamine Receptor. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Hexamethonium Bromide
A potent antagonist of nicotinic acetylcholine receptors (nAChRs) at pre-ganglionic sites in both the sympathetic and parasympathetic nervous systems.
MilliporeSigma™ Calbiochem™ Microcystin-RR, Microcystis aeruginosa
Arg-Arg analog of Microcystin-LR that is less toxic. Inhibits protein phosphatase 2A (IC50 = 3.4 nM). Useful for comparative structure and function studies.
MilliporeSigma™ Calbiochem™ Caspase Inhibitor, Negative Control
The Caspase Inhibitor, Negative Control, also referenced under CAS 105637-38-5, controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.